Utility of ST2 soluble biomarker in patients with atrial fibrillation and pulmonary veins isolation

Abstract Funding Acknowledgements Type of funding sources: Public hospital(s). Main source(s): No fundings related Background Atrial fibrillation (AF) is the more frequent arrhythmia in clinical practice and efficacy pulmonary vein ablation has being widely demonstrated. There still a lack information about predictive value electroanatomical voltage maps or biomarkers to predict recurrence. Purpose ST2 soluble (ST2S) biomarker previously analyzed by our group patients with AF electrical cardioversion demonstrating utility recurrence . So we sought analyze ST2S that underwent an electrophysiology study isolation (PVI) compare this biomarker. Results This was prospective, observational trial included total 156 who were referred hospital for PVI from September 2016 2019. We also 40 matched control initial analysis. All map sinus rhythm PVI. From PVI: 68 had paroxysmal 88 persistent. mean (13178.5 pg/ml) no significant difference controls (11016.2 baseline association values patients. When type AF, persistent significantly higher level there elevation according heart rate (>100 bpm) (p 0.038). observed levels at 3 6 months follow-up The lower cases area wider but nor In multivariant analysis only LA index volume predictor follow-up. Conclusions consider even though levels, specially those undergoing PVI, generalized probably inflammation not